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KMID : 1101720180220040020
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Physical Activity and Nutrition
2018 Volume.22 No. 4 p.20 ~ p.31
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AmLexin, a Standardized blend of Acacia catechu and Morus alba, shows benefits to delayed onset muscle soreness in healthy runners
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Yimam Mesfin
Talbott Shawn M.
Talbott Julie A.
Brownell Lidia
Jia Qi
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Abstract
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Purpose: Sudden and exhaustive exercise causes muscle damage accompanied by oxidative stress and inflammation, leading to muscle fatigue and soreness. AmLexin contains a standardized blend of extracts from the heartwood of Acacia catechu and the root bark of Morus alba, and is known to possess antioxidant and anti-inflammatory properties. The aim of this study was to investigate the effects of this proprietary blend supplementation on muscular pain and redox balance in healthy runners, in comparison to a placebo.
Methods: A double-blind placebo-controlled clinical trial was carried out over 9 weeks in a single center. Thirty physically active male and female subjects within 18?70 years of age were randomized into AmLexin (mean age = 42.92 ± 2.48 and gender 7/5, male/female, respectively) and placebo (mean age = 41.15 ± 3.5 and gender 10/3, male/female, respectively) groups. Subjects were supplemented with 400 mg of AmLexin/day or a look-alike placebo during an 8-week training program, and for one week following a 13.1-mile half-marathon. Twenty-six subjects completed the 9-week supplementation trial.
Results: Results showed the AmLexin group experienced significantly lower levels of post-exercise pain on day 1?3 following the half-marathon compared to the placebo group. The AmLexin group also showed lower post-exercise oxidative stress and higher antioxidant capacity on days 1 and 6 following the half-marathon. These results demonstrated the rapid benefits of AmLexin on pain and oxidative stress within 1?6 days post-exercise.
Conclusion: Our data suggest that AmLexin could be a safe, effective botanical alternative for delayed onset muscle soreness.
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KEYWORD
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Delayed onset muscle soreness, Acacia catechu, Morus alba, inflammation, oxidative stress
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